Phenobarbital might interact with other medicine so it is best to refer to with your veterinarian if your pet is on other medication. Immediately after extended use, Phenobarbital may well induce significant liver impairment. Brand Identify

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phenobarbital, sodium oxybate. Possibly boosts effects of another by pharmacodynamic synergism. Contraindicated. Prescribing information and facts for sodium oxybate states coadministration with Liquor or sleeplessness medication is contraindicated thanks to additive CNS depression.

phenobarbital will lower the extent or outcome of propafenone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Mysterious.

Phenobarbital can also be utilized for other functions not mentioned in this article. It can be marketed per tablet. Phenobarbital demands a prescription from the veterinarian and is classified to be a routine IV managed material. For:

phenobarbital will lower the extent or influence of nitrendipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.

Barbiturates are pregnancy group D medicines and happen to be revealed to result in fetal damage if Utilized in Expecting individuals. This course of medication can cross the placental barrier and distribute throughout the fetal tissue with the very best concentrations during the liver, brain, and placenta.

phenobarbital will lessen the level or influence of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Effect of coadministering a solid CYP3A4 inducer with fedratinib has not been examined.

Exclusive Client Population – Dosage needs to be reduced while in the elderly or debilitated because these people could be additional delicate to barbiturates. Dosage really should be reduced for individuals with impaired renal perform or hepatic condition.

phenobarbital will lower the level or impact of losartan by affecting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Importance Unidentified.

Griseofulvin. Phenobarbital seems to interfere While using the absorption of orally administered griseofulvin, So lowering here its blood degree.